The unexpected news was confirmed by Chambers’ agent in a statement to The Guardian.
John Grant speaking to British publication said “We are very sad to announce the untimely death, from natural causes, of the acclaimed actress Emma Chambers.”
“Over the years, Emma created a wealth of characters and an immense body of work. She brought laughter and joy to many and we be greatly missed.”
Overseas, Chambers rose to fame by showing Alice Tinker in the BBC’s The Vicar of Dibley.
She received praise of Stateside in 1999 by performing the character of Honey – opposite Julia Roberts and Hugh Grant – in the above-mentioned romantic comedy.
Tweeted Grant in response to his former co-star’s passing:
“Emma Chambers was a hilarious and very warm person and of course a brilliant actress. Very sad news.”
British broadcaster Emma Freud, who is married to Notting Hill writer and producer Richard Curtis, also took to Twitter Saturday to express her sympathies, writing:
“Our beautiful friend Emma Chambers has died at the age of 53.
“We’re very very sad. She was a great, great comedy performer, and a truly fine actress. And a tender, sweet, funny, unusual, loving human being.”
Here is also Dawn French, her Vicar of Dibley co-star:
“Emma was a very bright spark and the most loyal and loving friend anyone could wish for. I will miss her very much…
“I loved her. A lot.”
Before making it big on television in 1994, Chambers worked for years as a stage actress.
She was asthmatic and had a serious allergy to animals, but it’s unknown if any of these characters played a role in her death.
In 2002, Chambers told The Telegraph that her allergy could leave her needing a steroid injection or being rushed to hospital.
She is survived by her husband of 27 years.
May Emma Chambers rest in peace.